Phospholipase a2 gene

Author: nnsf

August undefined, 2024

WebMar 8, 2024 · The sequences of mammalian phospholipases were collected in the database UniProt by entering the gene names PLA2G1B and PLA2G2A, considering only the ten curated entries for PLA2G1B, and the five curated entries plus five other entries in the case of PLA2G2A. ... The phospholipase A2 superfamily and its group numbering system. … WebMar 13, 2024 · In this study, the function of the patatin-like phospholipase gene in V. dahliae (VdPLP, VDAG_00942) is characterized by generating gene knockout and complementary mutants. ... Percudani, R.; Bonfante, P.; Ottonello, S. A nutrient-regulated, dual localization phospholipase A2 in the symbiotic fungus Tuber borchii. EMBO J. 2001, 20, 5079–5090 ...

OMIM Entry - * 603604 - PHOSPHOLIPASE A2, GROUP VI; PLA2G6

WebThis gene is a member of the secretory phospholipase A2 family. It is located in a tightly-linked cluster of secretory phospholipase A2 genes on chromosome 1. The encoded enzyme catalyzes the hydrolysis of membrane phospholipids to generate lysophospholipids and free fatty acids including arachidonic acid. WebPhospholipase A2 Gene PLA2G1B Status UniProtKB reviewed (Swiss-Prot) Organism Homo sapiens (Human) Amino acids 148 Protein existence Evidence at protein level Annotation … philippine life expectancy

PHOSPHOLIPASE A2 (PLA2) ENZYME PREPARATION FROM …

WebPhospholipase A2: hydrolyzes the glycerol-fatty acid ester in position 2. ... This gene encodes a phospholipase A 2 enzyme that plays a crucial role in mitochondrial membrane … WebMar 28, 2024 · PLA2B, the synovial phospholipase A2 described by Seilhamer et al. (1989), is a small molecular weight enzyme that is DTT-sensitive. PLA2B is secreted from cells, active in the micromolar to millimolar calcium concentration range that prevails in the extracellular medium, and active in inflammatory exudates. Web"Mouse group X secretory phospholipase A2 induces a potent release of arachidonic acid from spleen cells and acts as a ligand for the phospholipase A2 receptor". Arch. Biochem. Biophys. 381 (1): 31–42. doi: 10.1006/abbi.2000.1977. PMID 11019817. Degousee N, Ghomashchi F, Stefanski E, et al. (2002). philippine liberation wwii

Regulatory Functions of Phospholipase A2 - PubMed

PLA2-ALPHA Phospholipase A2 family protein

WebPLA2G7 phospholipase A2 group VII [ (human)] Gene ID: 7941, updated on 5-Aug-2024 Summary The protein encoded by this gene is a secreted enzyme that catalyzes the degradation of platelet-activating factor to biologically inactive products. Defects in this gene are a cause of platelet-activating factor acetylhydrolase deficiency. WebPhospholipase A2. Phospholipase A2 (PLA2) is one of a family of phospholipases, enzymes that hydrolyse phospholipids. From: Clinical Biochemistry: Metabolic and Clinical Aspects … philippine life insurance companyWebShort Description: The protein encoded by this gene is a member of the phospholipase A2 family (PLA2). PLA2s constitute a diverse family of enzymes with respect to sequence, function, localization, and divalent cation requirements. This gene product belongs to group II, which contains secreted form of PLA2, an extracellular enzyme that has a ... philippine light reaction regiment

"WebSep 13, 2024 · To this regard, various host phospholipase A2 enzymes have been described to specifically cleave and remove peroxidised phospholipids from membranes [60–62]. To address this hypothesis, we performed a redox phospholipidomic approach to determine if ExoU could interfere with the endogenous levels of peroxidised phospholipids ( Figs … " - Phospholipase a2 gene

Phospholipase a2 gene

Human Secretary Phospholipase A2 Mutations and Their Clinical …

WebDec 18, 2024 · Phospholipase A2 group VI (PLA2G6)-associated neurodegeneration (PLAN) includes a series of neurodegenerative diseases that result from the mutations in PLA2G6. PLAN has genetic and clinical heterogeneity, with different mutation sites, mutation types and ethnicities and its clinical phenotype is different. WebMar 28, 2024 · In a Serbian brother and sister with GURDP, Brooke et al. (2014) identified a homozygous 4-bp deletion in the PLA2G4A gene ( 600522.0004 ). The mutation, which …

Did you know?

WebMay 12, 2024 · Ma, Z., Wang, X., Nowatzke, W., Ramanadham, S., Turk, J. Human pancreatic islets express mRNA species encoding two distinct catalytically active isoforms of group … WebMar 17, 2024 · The PLA2G6 gene encodes a group of VIA calcium-independent phospholipase A2 (iPLA2β) enzymes, which participate in various cellular functions, including phospholipid metabolism, membrane homeostasis, calcium signaling, apoptosis, and mitochondrial function. Thus, these functions could be perturbed by PLA2G6 gene …

WebCalf skeletal muscle gene expression of patients with PAD and healthy subjects was analyzed using microarrays. The top-ranking gene differentially expressed between PAD and controls (FDR < 0.001) was PLA2G16 , which encodes adipose-specific phospholipase A2 (AdPLA) and is implicated in the maintenance of insulin sensitivity and regulation of ... WebNov 16, 2015 · Astrocytic phospholipase A2 contributes to neuronal glutamate toxicity.pdf 2015-11-16 上传 Astrocytic phospholipase A2 contributes to neuronal glutamate toxicity

WebPLA2G2A (human) Gene Target - PubChem Apologies, we are having some trouble retrieving data from our servers... PUGVIEW FETCH ERROR: 403 Forbidden National Center for Biotechnology Information 8600 Rockville Pike, Bethesda, MD, 20894 USA Contact Policies FOIA HHS Vulnerability Disclosure National Library of Medicine National … WebCytogenetic location: 4q25 Genomic coordinates (GRCh38): 4:109,709,989-109,730,070 (from NCBI) TEXT Description Secreted phospholipase A2 (sPLA2) enzymes liberate arachidonic acid from phospholipids for production of eicosanoids and exert a variety of physiologic and pathologic effects.

WebCytosolic phospholipase A2 is an enzyme that in humans is encoded by the PLA2G4A gene. [5] [6] Function [ edit] This gene encodes a member of the cytosolic phospholipase A2 …

WebThe Val279Phe variant of the lipoprotein-associated phospholipase A2 gene is associated with catalytic activities and cardiovascular disease in Korean men. J Clin Endocrinol … philippine license renewal medical examWebMar 21, 2024 · GeneCards Summary for PLA2G2A Gene. PLA2G2A (Phospholipase A2 Group IIA) is a Protein Coding gene. Diseases associated with PLA2G2A include Familial … philippine license numberWebPhospholipase A2 (PLA2) catalyzes the hydrolysis of the sn-2 position of membrane glycerophospholipids to liberate arachidonic acid (AA), a precursor of eicosanoids including prostaglandins (PGs) and leukotrienes (LTs). The same reaction also produces lysophosholipids, which represent another class of lipid mediators. philippine lighting industry associationWebGene provides a unified query environment for genes defined by sequence and/or in NCBI's Map Viewer. LOC119581056 cytosolic phospholipase A2-like [ (black tiger shrimp)] Gene ID: 119581056, updated on 4-Feb-2024. Summary Other designations. LOW QUALITY PROTEIN: cytosolic phospholipase A2-like ... philippine library onlineWebAug 7, 2024 · PheneGene Graphics TEXT Description Phospholipase A2-activating protein (PLAA, or PLAP) is potentially important in regulating the inflammatory response through its activation of phospholipase A2 (e.g., 600522 ), which catalyzes the release of arachidonic acid ( Chopra et al., 1999 ). philippine liner shipping associationWebBackground Ureases are multifunctional enzymes that display biological activities independent of their enzymatic function, including exocytosis induction and insecticidal … philippine literacyWebDec 1, 2024 · Phospholipase is an enzyme that hydrolyzes ester bonds of glycerophospholipids; of these, phospholipases involved in the release of fatty acids are classified as phospholipase A (PLA). Furthermore, PLA is categorized into PLA1 and PLA2. trump finances investigated