Web10. aug 2003 · RER, calculated as the ratio of VCO 2 and VO 2, was slightly lower (0.7294 ± 0.003427 versus 0.7207 ± 0.002524; P < 0.05; Fig. 3b) in Cidea -null mice than in wild-type … Webphenotype (RER1) is a form of acquired genetic instability involved in tumour-suppressor-gene inactivation (Arzimanoglouet al., 1998) and was demonstrated in 2.5 to 44% of …
The metabolic footprint of aging in mice Scientific Reports - Nature
Web1. máj 1998 · The (A) 10 region and the (GT) 3 region in the TGF-β RII gene were screened to detect deletion and insertion. Deletions of A residue in the (A) 10 region were found in four samples, 11T, 22T, 26T, and 100T, which were 80% of the samples with severe RER (Fig. 1).Both alleles were deleted in the samples 22T, 26T and 100T, whereas 11T showed a … WebOnly one case showed an RER pheno- type. This case was excluded for further analysis because the RER phenotype corresponds to a quite different ge- netic lesion (mutations of DNA repair genes) by ... iron mountain mine redding ca
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WebAs a marker for the replication error phenotype (RER), microsatellite instability (MSI) has been commonly associated with endometrial carcinoma (22). In sporadic endometrial carcinoma, the MSI frequency varies, ranging from 15 to 45% (10,21,23). WebRER phenotype was detected in three (23%) cases, whereas germline p53 mutations were detected in none of 13 cases. A germline E-cadherin mutation was detected in one of … Web1. okt 1997 · Five cancers (20%) showed a RER phenotype and were associated with long survival of patients (32-96 months), whereas RER-negative cancers had a significantly poorer prognosis (Mantel-Cox test; P = 0.0084), with a … iron mountain missouri