WebJan 21, 2024 · The effects of low molecular weight fucoidan (LMWF) in combination with high-stability fucoxanthin (HSFUCO) on cardiac function and the metabolic pathways of aging mice ( Mus musculus ) were investigated. ... CREB and IRS1 proteins expression in the aging process. Three main metabolic pathways, namely the TCA cycle, glycolysis, and … WebApr 12, 2024 · Insulin receptor substrate 1 (IRS-1) is one of the major substrates of the insulin receptor kinase (1). IRS-1 contains multiple tyrosine phosphorylation motifs that …
IRS1 Gene - GeneCards IRS1 Protein IRS1 Antibody
WebMar 1, 2006 · IRS-1 was immunoprecipitated from an aliquot of the supernatant (500 μg), as described above for the PI 3-kinase analysis, and proteins were separated by SDS-PAGE. After transfer, membranes were probed with a polyclonal antibody against phospho-Ser (312) or phospho-Ser (616) (Cell Signaling). WebMolecular function Cellular component ... pathways: mice deficient of IRS1 have only a mild diabetic phenotype, but a pronounced growth impairment, i.e., IRS-1 knockout mice only reach 50% of the weight of normal mice. Regulation. The cellular protein levels of IRS-1 are regulated by the Cullin7 E3 ubiquitin ligase, ... old waste water treatment plant
Phospho-IRS-1 (Ser307) Antibody Cell Signaling …
WebMay 11, 2014 · WT, wild type; CS, C124S mutant; GE, G129E mutant; MW, molecular weight. (b) Western blot showing that WT PTEN, but not the CS or GE mutant, can inhibit EGF-induced AKT activation. GFP-S–tagged ... http://www.symansis.com/files/pdf/product/antibodies/DataSheet3023-P2_IRS1.pdf WebHonokiol, a hydroxylated biphenolic compound (C 18 H 18 O 2, molecular weight =266.33 kD) , is one of the major bioactive constituents of Magnolia bark (the traditional Chinese herbal drug, Hou Po) with the content of 1%–5% in the dried bark naturally. 12 In our previous study, we validated the antidiabetic activity of Magnolia bark. 13 ... is a fish a chordate