WebHowever, all of the EGFR inhibitors tested to date are associated with a number of dermatologic reactions because of the function of EGFR in skin biology. 5, 6 A distinct monomorphic papulopustular rash, which occurs in up to 50–100% of patients treated with anti-EGFR treatment, is the most frequently recorded side effect. 7-10 The rash is ... WebApr 27, 2016 · The EGFR inhibitor-induced papulopustular eruption has a stereotypical time course and occurs in a characteristic distribution affecting the central face, upper chest, and back. Bacterial superinfections more frequently affect the extremities, abdomen, and groin and may occur at any point during EGFR therapy.
EGFR Inhibitor–Associated Papulopustular Rash - The Journal of ...
WebIntroduction: Epidermal growth factor receptor (EGFR) inhibitors are established therapies for advanced lung, colorectal, and head and neck cancers. They commonly cause … http://site2024.jhoponline.com/issue-archive/2024-issues/jhop-march-2024-vol-7-no-1/17060-egfr-inhibitor-associated-papulopustular-rash dr smith\u0027s diaper rash ointment
EGFR Inhibitor–Associated Papulopustular Rash
WebJan 3, 2024 · The prophylactic or reactive treatment with tetracyclines for EGFR inhibitor-induced skin toxicity is currently clinical practice, though non-conclusive results are available. ... studies and more than 1,000 patients confirmed that the prophylaxis with tetracyclines is a protective factor for anti-EGFR-induced skin rash and positively … WebApr 7, 2024 · Epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) are widely used in the treatment of lung cancer, especially in the first-line treatment of advanced NSCLC, and EGFR-TKIs monotherapy has achieved better efficacy and tolerability compared with standard chemotherapy. ... EGFR-TKIs-induced rash/acne-like rash … dr smith\u0027s diaper rash spray