WebOct 6, 2015 · * Compound screening for drug discovery: screening for compounds that can specifically kill cancer stem cells. * 14 peer reviewed manuscripts published (4 first author; 10 Co-authorships) Show less WebJul 28, 2024 · Macrophages, a kind of innate immune cells, derive from monocytes in circulation and play a crucial role in the innate and adaptive immunity. Under the stimulation of the signals from local microenvironment, macrophages generally tend to differentiate into two main functional phenotypes depending on their high plasticity and heterogeneity, …
IKK Biology - PMC - PubMed Central (PMC)
WebAug 1, 2011 · In the preliminary study, ginsenoside Rb1, a main constituent of the root of Panax ginseng (family Araliaceae), and its metabolite compound K inhibited a key factor of inflammation, nuclear transcription factor κB (NF-κB) activation, in lipopolysaccharide (LPS)-stimulated murine peritoneal macrophages. When ginsenoside Rb1 or compound K … WebSep 1, 2024 · Ginsenoside Compound K Attenuates Ox-LDL-Mediated Macrophage Inflammation and Foam Cell Formation via Autophagy Induction and Modulating NF-κB, p38, and JNK MAPK Signaling … the call vegamovies
Ke Li - Research Investigator - Bristol-Myers Squibb LinkedIn
WebA gene on chromosome 9q31 that encodes a putative scaffold protein which may assemble active IKK-MAP3K14 complexes and act as subunit of the RNA polymerase II elongator … WebJan 1, 2024 · Compound K, a ginsenoside metabolite, plays an antiinflammatory role in macrophages by targeting the AKT1-mediated signaling pathway ... Macrophage-like … WebIKK-β-dependent phosphorylation of IRF-3 abrogates its transcriptional activity and stimulates further polyubiquitination and degradation mediated by E3 ubiquitin ligase cullin or RBCK1 [77,78]. M1 macrophages … the call vietsub 2020