Arf gap domain

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August undefined, 2024

Web15 apr 2006 · GIT1 and GIT2 domain structure. The full-length GIT proteins have an N-terminal ARF GTPase-activating protein (ARF-GAP) domain, three ankyrin (ANK) repeats, a Spa2-homology domain (SHD), a coiled-coil (CC) domain and a paxillin-binding site (PBS). The truncated GIT2-short protein lacks the CC domain and PBS. WebThe National Agricultural Library is one of four national libraries of the United States, with locations in Beltsville, Maryland and Washington, D.C.

ARF GTPases and their GEFs and GAPs: concepts and …

http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00105 Web1 dic 2010 · Interestingly, these studies showed that NEV/AGD5 shares substantial sequence similarity in the ARF GAP domain to the mammalian Arf GAPs SMAP1 and SMAP2, both of which directly interact with CHC ... company in tuas

Arf GAPs as Regulators of the Actin Cytoskeleton—An Update

Web29 mar 2024 · This gene encodes a member of a subfamily of ADP-ribosylation factor(Arf) GTPase-activating proteins that contain additional ankyrin repeat and pleckstrin … Web10 dic 2010 · AGAP1 (Arf GAP, GTPase, ankyrin repeat, PH) (also known as Centaurin-γ2) is an 89-kDa protein in both mouse and human cells that is expressed ubiquitously. It is a multi-domain protein comprised ... WebView（）/((3-Amino-1-hydroxypropane-1,1-diyl)bis(phosphonic acid)) information and documentation regarding ((3-氨基-1-羟基丙烷-1,1-二基)二膦酸 ... eazy ash

AGAP2: Modulating TGFβ1-Signaling in the Regulation of Liver …

ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 …

WebThe domain is organised around a central zinc atom which is coordinated by 4 cysteines. The ARFGAP domain is clearly unrelated to the other GAP proteins structures which are … Web19 feb 2024 · AGAP2 (Arf GAP with GTP-binding protein-like domain, Ankyrin repeat and PH domain 2) isoform 2 is a protein that belongs to the Arf GAP (GTPase activating protein) protein family. These proteins act as GTPase switches for Arfs, which are Ras superfamily members, being therefore involved in signaling … company in tucson azWebNie et al. (2002) found that AGAP1 showed strongest ARF-GAP activity toward ARF1 (), followed by ARF5 and ARF6 ().PtdIns(4,5)P2 and phosphatidic acid synergistically stimulated GAP activity. Point mutations of residues at or near the zinc finger of the ARF-GAP domain (cys594 and arg599, respectively) abolished ARF-GAP activity, and … company in ttdi

"Web12 apr 2024 · Auxin response factor (ARF) is an important transcription factor that regulates the expression of auxin-responsive genes by direct binding to their promoters, which play a central role in plant growth, development, and response to abiotic stresses. The availability of the entire Coix (Coix lacryma-jobi L.) genome sequence provides an opportunity to … " - Arf gap domain

Arf gap domain

Web25 nov 2008 · PTHR46021:SF5 ARF-GAP WITH DUAL PH DOMAIN-CONTAINING PROTEIN 1 1 hit; PTHR46021 ARF-GAP WITH DUAL PH DOMAIN-CONTAINING … Web19 set 2024 · ArfGAPs are a family of proteins containing an ArfGAP catalytic domain that induces the hydrolysis of GTP bound to the small guanine nucleotide-binding …

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Web11 apr 2024 · The amino acid sequence shows similarity with arf-GAP GTPase domain on performing a protein blast. (B) The orfs from the partner genes in the fusion transcript HOXD11 and AGAP3 along with their protein domains. Web24 mar 2009 · pthr45899:sf3 arf-gap with rho-gap domain, ank repeat and ph domain-containing protein 1 1 hit; pthr45899 rho gtpase activating protein at 15b, isoform c 1 hit; …

Web11 dic 2024 · Contacts between WDR41 and the DENN domain of SMCR8 drive the lysosomal localization of the complex in conditions of amino acid starvation. The structure suggested that C9ORF72-SMCR8 is a GTPase-activating protein (GAP), and Su et al. (2024) found that C9ORF72-SMCR8-WDR41 acts as a GAP for the ARF family of small … Web18 giu 2024 · Just a handful of ARF GAPs function without a canonical ARF GAP domain, including SEC23, the GAP for the ARF-related SAR1 GTPase, and the ELMO domain …

Web5 nov 1999 · The crystal structure of the PAPbeta ARF-GAP domain and the C-terminal ankyrin repeats has been determined at 2.1 A resolution. The ARF-GAP domain … WebWe have identified ARAP1 and ARAP2 and examined ARAP1 as a possible link between phosphoinositide-, Arf-, and Rho-mediated cell signaling. ARAP1 contains Arf GAP, Rho GAP, Ankyrin repeat, Ras-associating, and five PH domains. In vitro, ARAP1 had Rho GAP and phosphatidylinositol (3,4,5) trisphosphate (PIP3)-dependent Arf GAP activity. …

Web1 gen 2002 · ARAP1 is the first PH domain-containing Arf GAP found to associate with the Golgi apparatus. Overexpression of another Golgi-associated Arf GAP, Arf GAP1, causes loss of the Golgi apparatus and mixing of Golgi and endoplasmic reticulum proteins Aoe et al. 1997, Cukierman et al. 1995.

Web1 giu 2007 · In contrast, GAP IP4BP is constitutively membrane bound but requires binding of inositol 1,3,4,5 tetraphosphate, the PLC-mediated cleavage product of PIP3 to its PH domain for GAP activity (Cullen and Lockyer, 2002). β2-chimaerin, a GAP for Rac, contains an SH2 domain, a C1 domain responsible for DAG binding, and a RhoGAP domain. company intune appWeb28 nov 2002 · Function. Required for vesicle docking or fusion during acrosome biogenesis ( By similarity ). May play a role in RNA trafficking or localization. In case of infection by … company intune portal downloadWeb19 feb 2024 · AGAP2 (Arf GAP with GTP-binding protein-like domain, Ankyrin repeat and PH domain 2) isoform 2 is a protein that belongs to the Arf GAP (GTPase activating protein) protein family. These proteins act as GTPase switches for Arfs, which are Ras superfamily members, being therefore involved in signaling regulation. Arf GAP proteins … eazy assets private limited